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Psychedelics - Chemical Ocean Online Research chemical

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Most psychedelic drugs fall into one of the three families of chemical compounds: tryptamines, phenethylamines, or lysergamides. These chemicals all bind to serotonin 5-HT2A receptors, which modulate the activity of key circuits in the brain involved with sensory perception and cognition, however the exact nature of how psychedelics induce changes in perception and cognition via the 5-HT2A receptor is still unknown, although the fact that psychedelics reduce default mode network activity and increased connectivity between regions in the brain as a result is likely one of the most relevant pharmacological mechanisms underpinning the psychedelic experience, particularly ego death. The psychedelic experience is often compared to non-ordinary forms of consciousness such as those experienced in meditation, mystical experiences, and near-death experiences, which also appear to be partially underpinned by altered default mode network activity.